| Titel: | Induktion eines gemischten Chimärismus als Konsolidierungsimmuntherapie bei älteren Patienten mit akuter myeloischer Leukämie (AML) |
| Kurzbezeichnung: | Phase II – Studie AML > 55 Jahre |
| Studienleiter: | Prof. Dr. med. Dr. h.c. D. Niederwieser |
| Studienzentrale: | Universitätsklinikum Leipzig AÖR Zentrum für Innere Medizin Medizinische Klinik und Poliklinik II Abt. Hämatologie / Onkologie Johannisallee 32 04103 Leipzig Tel.: 0341/97130-51 Fax: 0341/97130-59 E-Mail: dietger@medizin.uni-leipzig.de |
| Rekrutierungszeitraum: | 12.01.1999 – 03.05.2005 |
| Nachbeobachtung: | laufend |
| Patienten (evaluierbar): | 41 |
| Publikation: | Hegenbart U, Lange T, Pönisch W, Sandmaier B, Maris M, Uharek L, Leiblein S, Edelmann J, Blume K, Niederwieser D, Storb R: Allogeneic hematopoietic stem cell transplantation (HSCT) from related and unrelated donors in patients with AML treated with 2 Gy total body irradiation (TBI) and posttransplant immunosuppression with ciclosporine (CSP) and mycophenolate mofetil (MMF). 27th Annual Meeting EBMT, March 25-28, 2001. Bone Marrow Transplantation 2001,27/S1:S283.
Hegenbart U, Lange T, Pönisch W, Sandmaier B, Maris M, Maloney D, Chauncey T, Uharek L, Leiblein S, Edelmann J, Greinix H, Niederwieser D, Storb R: Allogeneic hematopoitic stem cell transplants from related donors in patients with AML following minimal conditioning. Gemeinsame Jahrestagung in Mannheim, September 30-Oktober 3, 2001. Onkologie 2001,23/S1:218. Hegenbart U, Sandmaier B, Lange T, Pönisch W, Maris M, Maloney D, Leiblein S, Deininger M, Al-Ali H, Kliem C, Becker C, Hartung G, Möckel J, Chauncey T, Uharek L, Greinix H, Cordonnier C, Niederwieser D, Blume K, Storb R: Related and unrelated allogeneic hematopoietic stem cell transplants (HSCT) in patients with AML following minimal conditioning. 28th Annual Meeting EBMT, Montreux, Switzerland, March 24.-27.2002. Bone Marrow Transplantation 2002,29,S2:57. Hegenbart U, Krahl R, Kliem C, Rudoph M, Grommisch L, Pönisch W, Wedding U, Herold M, Subert S, Freund M, Fiedler F, Pasold R, Peter N, Meran j, Fasshauer E, Dachselt K, Grobe N, Assmann M, Kettner E, Steglich J, Huhn R, Schulze M, Schultze W, Ittel T, Klinkenstein C, Doepper J, Winkelmann C, Knauf W, Niederwieser D: Treatment of acute myeloid leukemia (AML) in patients older than 60 years: report of the AML-97-#38 study of the east german hematology and oncology study group (OSHO). Gemeinsame Jahrestagung in München, October 27. – 30.2002. Onkologie 2002,25,S4:18. Hegenbart U, Sandmaier B, Lange T, Poenisch W, Maris M, Maloney D, Leiblein S, Al-Ali H, Kliem C, Becker C, Grommisch L, Hartung G, Moeckel J, Chauncey T, Uharek L, Greinix H, Niederwieser D, Blume K, Storb R: Follow-Up of Allogeneic Hematopoietic Cell Transplantation (HCT) from Related and Unrelated Donors Following Minimal Conditioning in Patients with Acute Myelocytic Leukemia (AML). 44th ASH Annual Meeting, December 06. – 10.2002. Blood 2002,11, Part 1:76a. Hegenbart U, Sandmaier B, Lange T, Grommisch L, Pönisch W, Uharek L, Maris M, Maloney D, Leiblein S, Al-Ali H, Kliem C, Becker C, Hartung G, Chauncey T, Greinix H, Cordonnier C, Rio B, Gratwohl A, Niederwieser D, Blume K, Storb R: Allogeneic hematopoietic stem cell transplantation from related and unrelated donors in patients with acute myeloid leukemia following minimal conditioning. Gemeinsame Jahrestagung in Basel, October 4. – 8.2003. Onkologie 2003,26,S5:2. Niederwieser D, Hegenbart U, Sandmaier BM, Maris MB, Stuart M, Greinix H, Cordonnier C, Rio B, Gratwohl A, Lange T, Pönisch W, Grommisch L, Storer B, Maloney D, McSweeney P, Chauncey T, Agura E, Blume K, Storb R: Treatment for acute myelogenous leukemia by low dose irradiation based conditioning and hematopoietic cell transplantation from related and unrelated donors. 46th ASH Annual Meeting, December 4. – 7.2004. Blood 2004,104,S1:840a. Niederwieser D, Gentilini C, Hegenbart U, Lange T, Becker C, Wang SY, Bartsch K, Pönisch W, Raida M, Al-Ali H: Allogeneic stem cell transplantation (HCT) following reduced-intensity conditioning in patients with acute leukemias. Crit Rev Oncol Hematol 2005,56:275-281. Niederwieser D, Cross M, Lange T, Gentilini C, Haffner C, Pönisch W, Raida M, Al-Ali H: Hematopoietic cell transplantation in acute myeloid leukemia. Hematology 2005,1/1:128-132. Hegenbart U, Niederwieser D, Sandmaier BM, Maris MB, Shizuru JA, Greinix H, Cordonnier C, Rio B, Gratwohl A, Lange T, Al-Ali H, Storer B, Maloney D, McSweeney P, Chauncey T, Agura E, Epner E, Maziarz RT, Petersen F, Storb R: Treatment for acute myelogenous leukemia (AML) by low dose, total body, irradiation (TBI) based conditioning and hematopoietic cell transplantation (HCT) from related and unrelated donors. J Clin Oncol 2006,24:444-453. |
